Genotyping Psoriasis

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منابع مشابه

Identification of loci associated with late-onset psoriasis using dense genotyping of immune-related regions.

BACKGROUND Chronic plaque psoriasis can be subdivided into two groups according to the age of onset: type 1 (early onset, before 40 years) and type 2 (late onset, at or beyond 40 years). So far, 36 genetic loci have been associated with early-onset psoriasis in genome-wide association studies of white populations, while few studies have investigated genetic susceptibility to late-onset psoriasi...

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Nowadays stress is a normal part of everyday living and the physiological and behavioral consequences of exposure to stressful situations have been extensively studied for decades. The neuroendocrine stress response is a necessary mechanism but disrupts homeostatic process and it is subserved by a complex system located in both the central nervous system (CNS) and the periphery. Stressor-induce...

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An exome sequencing pipeline for identifying and genotyping common CNVs associated with disease with application to psoriasis

MOTIVATION Despite the prevalence of copy number variation (CNV) in the human genome, only a handful of confirmed associations have been reported between common CNVs and complex disease. This may be partially attributed to the difficulty in accurately genotyping CNVs in large cohorts using array-based technologies. Exome sequencing is now widely being applied to case-control cohorts and present...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2003

ISSN: 0022-202X

DOI: 10.1046/j.1523-1747.2003.12111.x